When Charlie saw that the queen was even leaving the most basic tactfulness behind, he knew that she had already been completely won over by the Rejuvenating Pill.
With her previous near-death experience, the Rejuvenating Pill would definitely become her only pursuit for the rest of her life.
So, Charlie would no longer have to worry about the queen having any bad thoughts or intentions toward Helena.
The queen would definitely do as she said and help Helena wield power with all of her might